The phytochemical analysis of the medicinal plant Moringa Oleifera was carried out to evaluate its antioxidant potential. Alcoholic and aqueous extracts of the leaves were subjected to in vitro antioxidant activity screening models such as inhibition of metal ion chelating activity, DPPH and ABTS scavenging activity. EDTA is used as a standard for metal ion chelating activity, Ascorbic acid is used as a standard. It can be deduced from the results obtained that the leaf extracts of Moringa Oleifera contains antioxidants capable of protecting normal cells from oxidative death, while rendering the cancer cells more susceptible to the cytotoxic action of the chemotherapeutic drug, etoposide, suggesting that the leaves of this plant can be administered as a supportive therapy during cancer chemotherapy, to minimize the toxic side effects to non-cancerous cells and to maximize the anticancer drug action. In all the models studied, the extracts showed potent antioxidant activity, thereby augmenting it into the present day system of medicine.
Key words: Phytochemical, antioxidant potential, chelating activity, supportive therapy.